I typically try to underestimate the norms in these situations. Under estimate on capacity, over estimate on current draw. helps account for real world dynamics.
And it's CCA, not OFC. It will handle temperatures better at the cost of conductivity. It naturally has it's own voltage drop, from my understanding. Plus I'm not sure where Cadence ranks in terms of wire. You got your 1/0 [which is really like 4 awg], "true 1/0", and then SHCA/Knu 1/0 which is closer to 2/0 imo. Obviously oversized has the advantage..but I think I'm getting sidetracked. Probably telling you what you already know anyway.
In short, You should be able to handle 4k fine assuming you have the actual electrical for it. 4k would be what? 400? 450 amps? In a perfect sine wave draw on an inefficient amp with soft clipping? Realistically, especially with rise doing it's thing, I wouldn't expect more than ~300 amps out of a 4K rms on the daily. and that's pushing it, imo. You should be fine.
Again. just speculation, someone feel free to correct me if I'm wrong.